New manuscript: Synthesis and comparison of Bub1 inhibitors

Congratulation to Ilma Amalina, not only has she successfully defended her PhD thesis but her thesis work is now available on Biorxiv. We have had a long standing interest in the Bub1, a serine/threonine kinase involved in both the spindle assembly checkpoint (SAC) and mitotic chromosome alignment. It is well documented that Bub1 phosphorylates Histone 2A at T120 (H2ApT120) which is required for recruitment of Sgo1 to centromeres. Small-molecule inhibitors are invaluable tool